IschemiaReperfusionInjury相关论文
Caspase-11 promotes NLRP3 inflammasome activation via the cleavage of pannexinl in acute kidney dise
Ischemia/reperfusion(I/R)injury is a major cause of acute kidney injury(AKI)in clinic.The activation of NLRP3 inflammaso......
缺血性卒中严重危害人类健康，是我国居民死亡或致残的首要病因，其早期干预治疗对改善患者预后极为重要。溶栓和血管内治疗为血管再通......
目的:探讨微小RNA-1（miR-1）对缺氧/复氧（H/R）心肌细胞凋亡的调节作用。方法:体外培养大鼠胚胎心脏组织来源心肌细胞株H9c2，将处于对数生......
Hypertrophic preconditioning attenuates myocardial ischemia/reperfusion injury through the deacetyla
To test the hypothesis that transient nonischemic stimulation of hypertrophy would render the heart resistant to subsequ......
Argon reduces microglial activation and inflammatory cytokine expression in retinal ischemia/reperfu
We previously found that argon exerts its neuroprotective effect in part by inhibition of the toll-like receptors (TLR) ......
Danshensu Ameliorates Cardiac Ischaemia Reperfusion Injury through Activating Sirt1/FoxO1/Rab7 Signa
Objective:To explore the specific molecular mechanisms of Danshensu (DSS) in the treatment of ischemia reperfusion injur......
Neutroprotective Efficacy of Sodium Tanshinone B on Hippocampus Neuron in A Rat Model of Focal Cereb
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Testicular torsion,a common urologic emergency,is primarily caused by ischemia/reperfusion (I/R) injury of the testis.Ni......
Diazoxide attenuates ischemia/reperfusion injury via upregulation of heme oxygenase-1 after liver tr
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Value of Susceptibility Weighted Imaging on Evaluation of Renal Ischemia Reperfusion Injury in Anima
Objective To evaluate the feasibility of SWI as a tool to identify the changes of renal outer medulla caused by ischemia......
Grape Seed Proanthocyanidin Protects Liver against Ischemia/Reperfusion Injury by Attenuating Endopl
Background: Liver ischemia/reperfusion (I/R) injury induces the occurence of endoplasmic reticulum (ER) stress.The immod......
Aim: To study the effects of genistein on isolated myocardial ischemia/reperfusion (I/R) injury rats and its effects on ......
Blockage of transient receptor potential vanilloid 4 alleviates myocardial ischemia/reperfusion inju
Transient receptor potential vanilloid 4(TRPV4)is a Ca2+-permeable nonselective cation channel and can be activated duri......
Protective effect of Shuangshenningxin preconditioning on mitochondrial function against ischemia/re
Aim: To investigate the effect of Shuangshenningxin (SSNX) on mitochondrial functional defects and metabolic derangement......
Myocardial infarction resulting from coronary atherosclerosis is the leading cause of death in modern society.Reperfusio......
The Washout with UW Solution and Tanshinone IIA to Decrease Ischemia Reperfusion Injury in Rat Ische
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Reactive oxygen species and Ca2+ signaling during myocardial ischemia/reperfusion injury and protect
Myocardial injury following ischemia/reperfusion (I/R) is a common clinical scenario in patients suffering from ischemic......
MicroRNA-25 (miR-25) has been reported to be a major miRNA marker in neural cells and is strongly expressed in ischemic ......
Notch signaling is essential for mesenchymal stem cell-mediated macrophage polarization in liver inf
Emerging evidence indicates that mesenchymal stem cells(MSCs)may regulate macrophage polarization.However,the underlying......
Myocardial injury following ischemia/reperfusion(I/R)is a common clinical scenario in patients suffering from ischemic h......
Ischemic Postconditioning During Reperfusion Attenuates Intestinal Mucosal Cell Apoptosis And Intest
Our previous study showed that apoptosis is the main mode of cell death induced by intestinal ischemia/reperfusion (I/R)......
Cardiopulmonary bypass (CPB) can induce myocardial ischemia reperfusion injury in patients undergoing open heart surgery......
Aim: The present study was designed to test the functional role of PDCD4 in cerebral ischemia reperfusion (I/R) injury a......
EFFECTS OF SELECTIVE Na+/H+ EXCHANGER CARIPORIDE ON ISOLATED LUNG ISCHEMIA AND REPERFUSION INJURY IN
Objective:To investigate the protective effects of selective Na+/H+ exchanger cariporide on isolated rat lung ischemia a......
THE EXPERIMENTAL RESEARCH OF PROTECTIVE MECHANISM OF LUNG ISCHEMIC PRECONDITIONING IN DEEP HYPOTHERM
Objective:To evaluate the protective effect of using lung IP prior to cardiac surgery with deep hypothermic circulatory ......
The Effect of Theanine on the Expression of Survivin, Bax,Caspase-3 in the Hippocampus and the Abili
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目的:观察缓激肽后处理对心肺复苏（CPR）大鼠的神经保护作用，并探讨其可能机制。方法:将48只成年雄性SD大鼠按随机数字表法分为假手术......
An emerging body of evidence indicates that transient receptor potential TRP channels act as important mediators for a w......
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Ischemic postconditioning alleviates lung injury and maintains a better expression of aquaporin-1 du
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背景： 脑卒中是仅次于缺血性心脏病的第二大疾病死亡原因，占全世界疾病死亡人数的9％。缺血性卒中是常见的卒中类型，因颈部或大脑的......
金属硫蛋白（metallothionein, MT）是一类富含半胱氨酸残基的低分子量金属连接蛋白，广泛存在于生物体内。心肌缺血/再灌注损伤（myocardi......
Hepatic stimulator substance confers resistance against hepatic ischemiareperfusion injury by improv
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目的观察4，4’-二异硫氰基芪_2，2’-二磺酸（4，4’-diisothiocyanostilbene-2，2’disulfonicacid，DIDS）对在体大鼠缺血／再灌注损伤（ischemia／r......
线粒体是细胞能量代谢的重要场所,并介导缺血（氧）诱导的细胞凋亡。存在于线粒体内膜上的线粒体膜通透性转换孔（mitochondrial permeab......
在临床上肺缺血-再灌注损伤(lung ischemiareperfusion injury,LIRI),可见于心肺分流术、肺移植、肺栓塞解除后等情况,其损伤程度......
Rac1 relieves neuronal injury induced by oxygen-glucose deprivation and re-oxygenation via regulatio
Certain microRNAs (miRNAs) can function as neuroprotective factors after reperfusion/ischemia brain injury. miRNA-142-3p......
Impaired Autophagy:A Mechanism of Fatty Liver Increases Susceptibility to Ischemia Reperfusion Injur
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Effects of phycocyanin on apoptosis and expression of superoxide dismutase in cerebral ischemia repe
BACKGROUND: The application of exogenous antioxidant is always the focus in the prevention and treatment of cerebral isc......
Effects of kallikrein gene transfer on penumbral microvascular proliferation and on regional cerebra
BACKGROUND: Recent findings have demonstrated that the kallikrein-kinin system (KKS) participates in the pathological pr......
Hyperlipidemia affects neuronal nitric oxide synthase expression in brains of focal cerebral ischemi
BACKGROUND: Hyperlipidemia, a risk factor for ischemic cerebrovascular disease, may mediate production of neuronal nitri......
Effect of nicorandil on infarct volume and marker enzyme activity in mitochondria of rats with cereb
BACKGROUND: Recent studies have suggested that mitochondrial ATP-sensitive K+ channel openers could reduce myocardium in......
Matrix metalloproteinase-9 expression and blood brain barrier permeability in the rat brain after ce
BACKGROUND: The integrity of the blood brain barrier (BBB) plays an important role in the patho-physiological process of......
Based on the hypothesis that upstream factor inhibition results in better treatment effects than downstream factor inhib......
Neuronal apoptosis and interleukin 1-beta converting enzyme expression in the frontal cortex and hip
BACKGROUND: Interleukin 1β-converting enzyme (ICE) gene expression can induce neuronal apoptosis. However, the dynamic ......
Propofol regulates Ca2+, Mg2+, Cu2+ and Zn2+ balance in the spinal cord after ischemia/reperfusion i
This study assessed concentrations of Ca2+, Mg2+, Cu2+ and Zn2+ in blood serum and spinal cord tissues, as well as the p......
Protective effect of propofol preconditioning and postconditioning against ischemic spinal cord inju
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The temporal expression of microRNA atfer spinal cord ischemia/reperfusion injury is not yet fully understood. In the pr......
Bone marrow mesenchymal stem cell therapy in ischemic stroke：mechanisms of action and treatment opti
Animal and clinical studies have conifrmed the therapeutic effect of bone marrow mesenchymal stem cells on cerebral isch......
